ARIMIDEXT 1 mg 30 Tabs (Anastrozole)
Anastrozole (Arimidex®) is the aromatase inhibitor of choice. The drug is used appropriately when substantial amounts of flavoring steroids are used, or when one is prone to gynecomastia and uses moderate amounts of such steroids. Arimidext does not have the side effects of aminoglutethimide (Cytadren®) and can achieve a very high estrogen blockade, I feel superior to Cytadren®. It is possible to reduce estrogen too much with Arimidext (up to 80%), and for this reason blood tests, or less preferably, salivary tests should be taken after the first week of use to determine if the dosage is correct. As an aromatase inhibitor, Arimidext's mechanism of action, which blocks the conversion of aromatizable steroids into estrogen, contrasts with the mechanism of action of antiestrogens such as clomiphene (Clomid®) or tamoxifen (Nolvadex®), both of which block estrogen receptors in some tissues and activate estrogen receptors in others. During a cycle, if you use Arimidext it is usually not necessary to use Clomid, but there may still be benefits to doing so.
Optimal dose: The dose of Arimidext ranges from .5 mg to 1 mg daily, depending on the cycle, propensity to gynecomastia, etc.
Side effects: Side effects with Arimidext are generally quite tolerable and will depend in part on the dose used and each particular user. Such effects may include headache, joint pains, feeling weak, increased blood pressure, swelling of the ankles or feet, mood swings, depression.
In conclusion, although there are more powerful antiestrogens, such as letrozole, which annihilate estrogens 100%, they are reserved for very particular cases and should not be used lightly, since reducing estrogen completely carries its own health risks. Arimidext should always be our first choice antiestrogen.